Time-Dependent Changes in Donor Brain Death Related Processes

Families of birth - death processes with similar time - dependent behaviour

We consider birth-death processes taking values in N ≡ {0, 1, . . .}, but allow the death rate in state 0 to be positive, so that escape from N is possible. Two such processes with transition functions {pij(t)} and {p̃ij(t)} are said to be similar if, for all i, j ∈ N , there are constants cij such that p̃ij(t) = cijpij(t) for all t ≥ 0. We determine conditions on the birth and death rates of a b...

Diagnosis of brain death and donor management.

Despite a widespread acceptance of organ transplant the world over, there is still a lack of conceptual clarity about brain death in severely injured cases. The use of terminology “brain death instead of death creates confusion in the mind of few people that it is only the brain and not the patient that is dead. Health professionals have personal concepts of death that vary widely. In one of th...

Brain death, cardiac death, and the dead donor rule.

Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts.

BACKGROUND Brain death (BD) can immunologically prime the donor organ and is thought to lead to exacerbated ischemia/reperfusion injury after transplantation. Using a newly developed mouse model of BD, we investigated the effect of donor BD on posttransplantation cardiac ischemia/reperfusion injury. We further investigated the therapeutic effect of a targeted complement inhibitor in recipients ...

An algebraic calculation method for describing time-dependent processes in electrochemistry – Expansion of existing procedures

In this paper an alternative model allowing the extension of the Debye-Hückel Theory (DHT) considering time dependence explicitly is presented. From the Electro-Quasistatic approach (EQS) introduced in earlier studies time dependent potentials are suitable to describe several phenomena especially conducting media as well as the behaviour of charged particles (ions) in electrolytes. This leads t...